A comparison of co-codamol and modified-release morphine sulphate for step-down analgesia in patients following thoracotomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN52893628

Enrollment

Registered

2007-09-28

Start date

2006-06-21

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Signs and Symptoms: Pain Signs and Symptoms Pain

Interventions

Patients undergoing thoracotomy for the first time and not taking regular analgesia for another condition can be considered for this study. Analgesia in the immediate post-operative period will be d

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients >18 years 2. First-time thoracotomy patient 3. Informed consent

Exclusion criteria

Exclusion criteria: 1. Patients <18 years 2. Pregnancy 3. Breast-feeding 4. Not able to give informed consent 5. Already taking analgesia at time of admission

Design outcomes

Primary

Measure	Time frame
1. Adequacy of pain control as measured by the visual analogue scale (0=no pain, 10=excruciating) 2. How frequently breakthrough analgesia is used overall satisfaction of pain control	—

Secondary

Measure	Time frame
Complications: nausea/vomiting, sedation, constipation, pruritis, mobility and compliance	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026