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The use of a randomised controlled trial of autologous stem cell transplantation (ASCT) versus mobilisation alone to investigate the pathogenic role of T-cells in patients with severe rheumatoid arthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN52892553
Enrollment
Unknown
Registered
2003-09-12
Start date
2001-12-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Musculoskeletal Diseases: Rheumatoid arthritis (RA) Musculoskeletal Diseases

Interventions

Laboratory study
Randomised controlled trial, Random allocation to: A. Autologous stem cell transplantation B. Mobilisation alone

Sponsors

Record provided by the NHS Trusts Clinical Trials Register - Department of Health (UK)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with rheumatoid arthritis who have failed conventional therapy. Patients will be enrolled from specialist RA clinics.

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

MeasureTime frame
RA quality of life questionnaire, health assessment questionnaire. Tender and swollen joint counts. Inflammatory markers. Histological analysis.—

Secondary

MeasureTime frame
Not provided at time of registration—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026