Treatment of functional symptoms due to work-related stress

A randomised controlled trial of a immediate versus delayed stress management program versus traditional psychological therapy in adults suffering from work-related stress symptoms

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN52839015

Enrollment

210

Registered

2010-04-15

Start date

2010-05-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stress, adjustment disorders Mental and Behavioural Disorders Reaction to severe stress, and adjustment disorders

Interventions

This study will analyse the effect of a stress management program. The program is composed of: 1. Stress management therapy 2. Mindfulness therapy 3. Dialogue with the participants workplace/employer

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Adults aged 18 - 64 years, either sex 2. Employed 3. On sick leave 4. Moderate to high stress symptom score

Exclusion criteria

Exclusion criteria: 1. If alcohol or substance abuse has contributed substantially to the load condition 2. Unemployment 3. Major illnesses for example cancer and heart diseases, which has contributed substantially to the load condition 4. Physically impaired abilities, which prevent physical activity as a fast walk 5. Major mental disorder

Design outcomes

Primary

Measure	Time frame
Return to work rate, measured at 4 months and one year.	—

Secondary

Measure	Time frame
1. Symptom Checklist 92, measured at 4 months 2. World Health Organization (WHO) Major Depression Inventory, measured at 4 months 3. Absenteeism, measured at 4 months 4. Copenhagen Psychosocial Questionnaire (COPSOQ), measured at 4 months 5. Objective measures: 5.1. Salivary cortisol, measured at 4 months 5.2. High density lipoprotein (HDL) cholesterol, total cholesterol, blood pressure, measured at 4 months 5.3. C-reactive protein (CRP) and interleukin-6 (IL-6) (immunological status), measured at 4 months 5.4. HbA1C and dehydroepiandrosterone sulfate (DHEA-S) (metabolic condition), measured at 4 months 5.5. Heart rate variability (HRV), measured at 4 months 5.6. Neo Pi-r Personality Inventory (personality testing), measured at baseline	—

Measure

Time frame

1. Symptom Checklist 92, measured at 4 months 2. World Health Organization (WHO) Major Depression Inventory, measured at 4 months 3. Absenteeism, measured at 4 months 4. Copenhagen Psychosocial Questionnaire (COPSOQ), measured at 4 months 5. Objective measures: 5.1. Salivary cortisol, measured at 4 months 5.2. High density lipoprotein (HDL) cholesterol, total cholesterol, blood pressure, measured at 4 months 5.3. C-reactive protein (CRP) and interleukin-6 (IL-6) (immunological status), measured at 4 months 5.4. HbA1C and dehydroepiandrosterone sulfate (DHEA-S) (metabolic condition), measured at 4 months 5.5. Heart rate variability (HRV), measured at 4 months 5.6. Neo Pi-r Personality Inventory (personality testing), measured at baseline

—

Countries

Denmark

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026