A multidisciplinary approach to identify and analyse not only the causes but also the risk factors for increased mortality in invasive infections caused by Streptococcus pyogenes

A multidisciplinary investigation of molecular mechanisms and clinical risk factors predicting increased mortality in invasive Streptococcus pyogenes infections

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN52769435

Enrollment

Registered

2026-04-24

Start date

2025-05-23

Completion date

Unknown

Last updated

2026-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Streptococcus pyogenes infection Infections and Infestations

Interventions

This is a multicentre, prospective, non-interventional cohort study. The enrolment will take place in three centres in the Czech Republic. We plan to enrol 300 adult patients in total. Patients over 1

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Aged >18 years 2. Invasive S. pyogenes infections 3. Skin and soft tissue infections caused by S. pyogenes

Exclusion criteria

Exclusion criteria: 1. Aged <18 years 2. Other bacterial finding in blood cultures and clinically valid samples than S. pyogenes

Countries

Czech Republic

Contacts

Public ContactGabriela Kronieslová

gabriela.kroneislova@vfn.cz+420 (0)224967265

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: May 7, 2026