To study ciprofloxacin pharmacokinetics in patients who are critically ill and undergoing continuous dialysis

An evaluation of ciprofloxacin pharmacokinetics in critically ill patients undergoing continuous veno-venous haemodiafiltration

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN52722850

Enrollment

Registered

2011-05-19

Start date

2005-01-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients on dialysis Nutritional, Metabolic, Endocrine Renal failure

Interventions

1. Timed serum samples were collected during each dosage interval and ultrafiltrate during 7 dosage intervals (1 per patient) 2. Effluent fluid was collected for the entire dosage interval 3. The volu

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged over 18 2. Requiring Continuous Veno Venous Hemodiafiltration (CVVHDF) 3. Requiring ciprofloxacin therapy

Exclusion criteria

Exclusion criteria: 1. Aged less than 18 2. Patient / relative consent denied

Design outcomes

Primary

Measure	Time frame
To obtain reliable estimates of ciprofloxacin pharmacokinetic parameters for patients in intensive care unit (ICU) on Continuous veno-venous hemodiafiltration (CVVHDF)	—

Secondary

Measure	Time frame
To describe achieved pharmacodynamic parameters in these patients	—

Countries

Ireland

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 28, 2026