Coronary artery bypass graft surgery Circulatory System Coronary artery bypass graft surgery
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients admitted to the Yonsei University Health System scheduled for isolated off-pump coronary artery bypass graft surgery between August 2006 and March 2007.
Exclusion criteria
Exclusion criteria: 1. Patients undergoing emergent surgery 2. Pre-existing neurologic disease 3. Lung parenchymal disease 4. New York Heart Association (NYHA) functional class >= 3 5. Left ventricular ejection fraction <40% 6. Unstable angina and recent myocardial infarction within 1 month 7. Patients who had significant luminal narrowing of either carotid and/or vertebral arteries on preoperative angiography
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Regional cerebral oxygen saturation measured by near infrared spectroscopy | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic variables including the following: 1. Cardiac index (CI) 2. Mixed venous oxygen saturation 3. Mean arterial pressure 4. Central venous pressure | — |
Countries
Korea, South