FindTrial
Sign In

Trial of pre-operative chemotherapy in biopsy proven Wilms tumour versus immediate nephrectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN52591297
Enrollment
Unknown
Registered
2001-07-01
Start date
1991-10-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney, solid tumour of childhood Cancer Kidney

Interventions

1. Treatment A: Immediate surgery, nephrectomy 2. Treatment B: Tumour biopsy and pre-operative chemotherapy followed by nephrectomy

Sponsors

Cancer Research UK (CRUK) (UK)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Over 6 months and under 16 years of age at diagnosis 2. Clinical and radiological evidence of Wilm's tumour 3. No previous treatment for Wilm's tumour 4. Tumour is deemed operable 5. No evidence of metastases

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

MeasureTime frame
Not provided at time of registration—

Secondary

MeasureTime frame
Not provided at time of registration—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026