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Hybrid single-photon emission computed tomography?computed tomography (SPECT-CT) imaging results in chronic low back pain patients as compared to an asymptomatic control group

Evaluation of the prevalence of increased Phosphorus uptake at lumbar level during SPECT-CT in a group of patients with low back pain as compared to an asymptomatic a control group

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN52513588
Enrollment
200
Registered
2014-02-17
Start date
2013-08-08
Completion date
Unknown
Last updated
2020-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sensitivity of SPECT-CT in the identification of the pain phenotype when analyzing chronic low back pain Musculoskeletal Diseases Chronic low back pain

Interventions

Patients with chronic low back pain (more than 3 months) are referred for SPECT-CT imaging. In the control group, the patients were referred for SPECT-CT for other reasons than chronic low back pain.

Sponsors

AZ Nikolaas
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients older than 18 years 2. Referred to the department of medical imaging for SPECT-CT 3. Having signed the informed consent

Exclusion criteria

Exclusion criteria: 1. Recent vertebral fractures 2. History of lumbar spine surgery 3. Diagnosed malignancy 4. Pregnancy 5. Contraindication for injection 99mTc hydroxymethane diphosphonate (99MTc-HDP)

Design outcomes

Primary

MeasureTime frame
Number of patients with ?hotspots? on SPECT-CT in the group with chronic low back pain, compared to the number of patients with ?hotspots? on SPECT-CT in the group without chronic low back pain.

Secondary

MeasureTime frame
Analysis of the structures that show activity in both groups. The SPECT-CT images are read by the neuroradiologist immediately after the investigation. As the value of SPECT-CT as diagnostic tool for spinal pain is measured the interpretation of the images is done only once.

Countries

Belgium

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026