Analgesia provided by intravenous paracetamol compared with intravenous morphine, for pain secondary to isolated limb trauma, in the emergency department: a pilot randomised trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN52451941

Enrollment

Registered

2007-08-29

Start date

2007-09-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Isolated limb trauma Signs and Symptoms Isolated limb trauma

Interventions

Intravenous paracetamol (1 g) or intravenous morphine (10 mg).

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Isolated limb trauma 2. Moderate to severe pain, with initial verbal pain score of 7 or more 3. Age >15 and 50 kg

Exclusion criteria

Exclusion criteria: 1. Chest pain 2. Glasgow Coma Scale (GCS) 65 years 10. Patients in extreme distress who are unable to consent 11. Communication difficulties (foreign language, prior confusion) preventing informed consent or co-operation with pain scoring

Design outcomes

Primary

Measure	Time frame
Visual analogue pain score, measured at 0, 5, 15, 30 and 60 minutes (the drug infusion starts at time 0).	—

Secondary

Measure	Time frame
1. Requirement for rescue morphine 2. Patient satisfaction of overall analgesia on five point likert scale at 60 minutes 3. Occurence of side effects	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026