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Working memory in children with attention-deficit/hyperactivity disorder (ADHD): the impact of methylphenidate (MPH)

Working memory in children with attention-deficit/hyperactivity disorder (ADHD): the impact of methylphenidate (MPH)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN52376787
Enrollment
60
Registered
2004-01-23
Start date
1998-09-01
Completion date
Unknown
Last updated
2020-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Behavioural disorders Mental and Behavioural Disorders Hyperkinetic disorders

Interventions

1. Methylphenidate (MPH) treatment 2. No methylphenidate treatment

Sponsors

NHS R&D Regional Programme Register - Department of Health (UK)
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 60 boys aged between 7-12 years, receiving MPH, with a diagnosis of Hyperkinetic disorder or the equivalent ADHD combined sub-type, will be recruited from out-patient psychiatric clinics in the Trent region.

Exclusion criteria

Exclusion criteria: Does not match inclusion criteria

Design outcomes

Primary

MeasureTime frame
1. Information about effects of MPH on cognitive function (including the possibility of cognitive toxicity) in children with ADHD 2. Greater understanding of the underlying cognitive processes in ADHD This knowledge of underlying mechanisms will lead to improved specificity of early detection, diagnosis and treatment of ADHD 3. Identification of potential cognitive deficits in ADHD. If persisting cognitive deficits are identified. These will be rational targets for supplementary treatment interventions 4. Suggestion of tests to monitor the effects of MPH on cognitive function which could be developed for use in everyday clinical practice.

Secondary

MeasureTime frame
Not provided at time of registration

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026