Skip to content

Electrical stimulation after nerve repair to enhance regeneration

The effectiveness of a new treatment for patients with peripheral nerve injuries in the upper limb

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN52307835
Enrollment
150
Registered
2013-09-04
Start date
2013-08-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peripheral nerve injury Injury, Occupational Diseases, Poisoning Injury of peripheral nerve(s) of abdomen, lower back and pelvis

Interventions

Intervention: Post surgical electrical stimulation Controls: Surgery alone. Duration: The electrical stimulation will last for 1 hour. Total follow up length is 2 years.

Sponsors

University of Alberta (Canada)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients (both male and female over the age of 18 years) with severe injury to the nerves in the upper arm, forearm or hand causing denervation.

Exclusion criteria

Exclusion criteria: 1. Other injuries that would impair hand function. 2. The presence of other neurologic conditions. 3. Cognitive compromise that renders the patients unable to understand and consent to the study. 4. Minors younger than the age of 18.

Design outcomes

Primary

MeasureTime frame
1. Motor unit number estimation - Nerve conduction studies to determine motor nerve regeneration. 2. Quantitative sensory testing to determine sensory nerve regeneration All outcomes measured at baseline, 3 months, 6 months, 9 months, 12 months, 18 months, 24 months

Secondary

MeasureTime frame
1. Symptom severity scales - Questionnaires to determine change in symptom severity 2. Hand functional evaluation - Hand function tests to determine strength and dexterity All outcomes measured at baseline, 3 months, 6 months, 9 months, 12 months, 18 months, 24 months

Countries

Canada

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026