Cost and efficacy of dissection devices in extended and parenchyma preserving liver resection: a prospective randomised trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN52294555

Enrollment

Registered

2008-08-28

Start date

2003-09-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary or secondary hepatic malignacy Cancer Malignant neoplasm of liver and intrahepatic bile ducts

Interventions

Liver resection with three different liver resection (dissection) devices: 1. Selector® (Erbe, Tübingen, Germany) 2. Helix HydroJet® (Erbe, Tübingen, Germany) 3. Dissecting Sealer 3.0® (TissueLink Med

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients undergoing liver resection for primary or secondary hepatic malignancy of any age and gender.

Exclusion criteria

Exclusion criteria: 1. Cirrhosis or cholestasis (serum bilirubin greater than 25 mg/dl) 2. Prior chemotherapy (within 6 months) and multiple liver tumours

Design outcomes

Secondary

Measure	Time frame
1. Mounting time 2. Costs of devices (system costs) 3. Maintenance costs 4. Costs of additional haemostyptic items 5. Costs of staplers and magazines Primary and secondary outcomes were measured during the hospital stay.	—

Primary

Measure	Time frame
1. Blood loss 2. Intraoperative and postoperative blood transfusions 3. Dissection time 4. Resection area 5. Dissection speed 6. Blood loss per dissected area 7. Post-operative International Normalised Ratio (INR) 8. Post-operative partial thromboplastin time (PTT) 9. Post-operative bilirubin levels 10. Morbidity (bleeding, bile fistula, cholangitis, liver abscess, pleura effusion, pneumonia, cardiac complications) 11. Intensive Care Unit (ICU) stay 12. Hospital stay Primary and secondary outcomes were measured during the hospital stay.	—

Measure

Time frame

1. Blood loss 2. Intraoperative and postoperative blood transfusions 3. Dissection time 4. Resection area 5. Dissection speed 6. Blood loss per dissected area 7. Post-operative International Normalised Ratio (INR) 8. Post-operative partial thromboplastin time (PTT) 9. Post-operative bilirubin levels 10. Morbidity (bleeding, bile fistula, cholangitis, liver abscess, pleura effusion, pneumonia, cardiac complications) 11. Intensive Care Unit (ICU) stay 12. Hospital stay Primary and secondary outcomes were measured during the hospital stay.

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Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 2, 2026