The CIRCLE Trial - Cerclage in Relation to Cervical LEngth. A clinical study to determine the effects of cervical scanning and cervical stitches in preventing preterm labour

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN52175236

Enrollment

1890

Registered

2005-01-17

Start date

2003-11-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preterm labour Pregnancy and Childbirth Preterm labour

Interventions

Intervention group: Therapeutic cervical suture if cervical canal shortens to =20 mm Control group: Elective cervical suture will only be inserted if the past obstetric history is suggestive of cervi

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Pregnant women at high risk of preterm labour. Eligibility criteria: any pregnant woman, with a singleton pregnancy, between 16-24 weeks of pregnancy, with a history of one or more previous spontaneous deliveries prior to 34 weeks.

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
Not provided at time of registration	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026