Postnatal depression Mental and Behavioural Disorders Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified
Conditions
Sponsors
University College London
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Feasibility trial: 1. Aged 18 years or older 2. Female 3. Postnatal depression as indicated by a score of 12 or more on the PHQ-9 at baseline 4. Mother with an infant aged 6 - 35 weeks old at the time of screening Conceptual mapping: Lebanon inclusion criteria: 1. Mothers who have recently given birth, living in one of the two research sites, of Palestinian, Syrian or Lebanese nationality 2. Fathers who have recently had a child, living in one of the two research sites, of Palestinian, Syrian or Lebanese nationality 3. Healthcare workers without mental health expertise, who work in one of the two research sites 4. Healthcare workers with mental health expertise, who work in one of the two research sites 5. Religious leaders from the Sunni, Shi'a, Christian, Druze communities, working in one of the two research sites 6. Key informants, such as staff working in local or national organisations in a related field (mental health, maternal health and early childhood health) Kenya inclusion criteria: 1. Mothers who have recently given birth, living in one of the two research sites 2. Fathers who have recently had a child, living in one of the two research sites 3. Healthcare workers without mental health expertise, who work in one of the two research sites 4. Healthcare workers with mental health expertise, who work in one of the two research sites 5. Religious leaders working in one of the two research sites 6. Traditional midwives working in one of the two research sites 7. Key informants, such as staff working in local or national organisations in a related field (mental health, maternal health and early childhood health)
Exclusion criteria
Exclusion criteria: Feasibility trial: 1. Mothers with psychotic conditions including bipolar disorder, anorexia nervosa or substance dependency 2. Mothers whose babies have severe physical health problems or neurodevelopmental problems Conceptual mapping: 1. Mothers with psychotic conditions including bipolar disorder, anorexia nervosa or substance dependency 2. Mothers whose babies have severe physical health problems or neurodevelopmental problems
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of depression measured using the Patient Health Questionnaire – depression module (PHQ-9) at baseline and at 8 (T2), 13 (T3), and 24 (T4) weeks post-treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Family circumstances assessed using the family circumstances questionnaire at baseline (T1) and 13 weeks (T3) 2. Height and weight measures of infants following WHO guidelines at baseline (T1) and 13 weeks (T3) 3. Early childhood development outcomes measured using the Caregiver Reported Early Development Index (CREDI) long form at baseline (T1), 8 weeks (T2), 13 weeks (T3) and 24 weeks (T4) 4. Depression measured using the Hamilton Depression Rating Scale (HRSD) at baseline (T1), 8 weeks (T2), 13 weeks (T3) and 24 weeks (T4) 5. Anxiety measured using the General Anxiety Disorder-7 (GAD-7) at baseline (T1), 8 weeks (T2), 13 weeks (T3) and 24 weeks (T4) 6. Sleep measured using the Sleep Condition Indicator (SCI) at baseline (T1), 8 weeks (T2), 13 weeks (T3) and 24 weeks (T4) 7. Generic health status measured using the Short-Form Health Survey (SF-36) at baseline (T1), 8 weeks (T2), 13 weeks (T3) and 24 weeks (T4) 8. Alcohol consumption measured using the Alcohol Use Disorders Identification Test (AUDIT) at baseline (T1) and 13 weeks (T3) 9. Infant’s sleep measured using the Brief Infant Sleep Questionnaire – Revised Short form (BISQ) at baseline (T1), 8 weeks (T2), 13 weeks (T3) and 24 weeks (T4) 10. Infant’s physical health measured using the infant physical health questionnaire at baseline (T1), 8 weeks (T2), 13 weeks (T3) and 24 weeks (T4) 11. Infant’s cognitive development measured using the Malawi Developmental Assessment Tool (MDAT) at 24 weeks (T4) 12. Breastfeeding assessed using the breastfeeding outcome measure at baseline (T1), 8 weeks (T2), 13 weeks (T3) and 24 weeks (T4) 13. Social isolation assessed using the Lubben Social Network Scale (LSNS-6) at baseline (T1) and 13 weeks (T3) 14. Relationship satisfaction measured using the Couple Satisfaction Index (CSI-16) at baseline (T1) and 13 weeks (T3) 15. Health outcome assessed using EQ-5D at baseline (T1) and 13 weeks (T3) 16. Capability measured using the ICEpop CAPability measure for Adults (ICECAP-A) | — |
Countries
Kenya, Lebanon
Contacts
Public ContactElizabeth Simes
Outcome results
None listed