A multicenter double blind randomised clinical cost-effectiveness trial. Microendoscopic lumbar discectomy versus conventional microsurgery. Blind for patient and research-nurse.

Conditions

Sciatica Nervous System Diseases Dorsalgia

Gijsbert M. Overdevest, Wilco C. Peul, Ronald Brand, Bart W. Koes, Ronald Bartels et al. (7 authors)

Journal of Neurology Neurosurgery & Psychiatry2017-05-2673 citations

10.1136/jnnp-2016-315306

Effect modifiers of outcome of surgery in patients with herniated disc related sciatica? A subgroup analysis of a randomised clinical trial.

Arts MP, Brand R, Koes BW, Peul WC.

2010-06-1410 citations

10.1136/jnnp.2009.192906

Tubular diskectomy vs conventional microdiskectomy for sciatica: a randomized controlled trial.

Arts MP, Brand R, van den Akker ME, Koes BW, Bartels RH, Peul WC, Leiden-The Hague Spine Intervention Prognostic Study Group (SIPS).

2009-07-01141 citations

10.1001/jama.2009.972

Interventions

Randomisation in operation room to: 1. Microendoscopic surgery 2. Conventional microsurgery

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients (18-70 years) with at least 8 weeks sciatica not reacting to conservative treatment. An indication for surgery is made by the clinical picture with MRI confirmation of a lumbar disc herniation.

Exclusion criteria

Exclusion criteria: Does not match inclusion criteria

Design outcomes

Primary

Measure	Time frame
Roland Disability Questionnaire for Sciatica (RDQ)	—

Secondary

Measure	Time frame
1. Perceived recovery 2. Visual anolog scale (VAS) 3. VAS of back pain and combined leg and back pain 4. McGill pain questionnaire 5. Short-Form-36 questionnaire (SF 36) 6. Sciatica frequency and bothersome index (SFBI) 7. Prolo scale	—

Countries

Netherlands

Outcome results

None listed