Young People (14-35 years) with first-episode psychosis (F20-F29
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Consecutive referrals to the EIP service during the study recruitment period aged 14-35 years 2. Meeting criteria for a first episode of psychosis (FEP) as determined by each local service according to their own established criteria. The inclusion criteria used to make these decisions will be recorded for each service, and made available for subsequent inspection
Exclusion criteria
Exclusion criteria: 1. A sub-threshold ‘at risk mental state’, not meeting first episode of psychosis criteria 2. Referral over the age of 35 3. Referrals where there is remaining diagnostic uncertainty about psychosis at 12 months 4. Participants will be withdrawn from the study if (i) they move to a mental health service outside the study or (ii) they move to a service that is in a different arm of the EYE project
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to disengagement: time in days from date of allocation to care coordinator to date of last contact following refusal to engage with EIP service, or lack of response to EIP contact for a consecutive 3-month period | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes include mental health, social & occupational function, recovery and satisfaction: 1. Mental health, social and occupational function is measured with the Health of the Nation Outcome Scale (HoNOS) clinician-rated at baseline, 6, 12 (18 and 24 months or until end of study if this is sooner) 2. Recovery is measured by the Questionnaire on the Process of Recovery (QPR) patient-rated at baseline, 6, 12 (18 and 24 months or until end of study if this is sooner) 3. Satisfaction measured by the DIALOG questionnaire at baseline, 6, 12 (18 and 24 months or until end of study if this is sooner) Process evaluation questionnaire data will be collected from all consenting clinicians at three timepoints: 1. An Adapted NOMAD questionnaire will measure attitudes and approaches towards implementation at start, mid and end of the intervention 2. Fidelity will be measured using a bespoke EYE-2 fidelity checklist at start, mid and end of intervention delivery Implementation will also be evaluated qualitatively using a brief semi-structured interview to explore barriers and facilitators to intervention delivery, including context and turbulence, across thee timepoints at start, mid and end of the intervention. Finally, the cost-effectiveness analysis will utilise the: 1. Societal costs measured with the Adult Service Use Schedule collected at 12 months 2. NHS costs measured by case-note data on service use for the period from baseline to 12 months, and by the HoNOS questionnaire data at baseline and 12 months | — |
Countries
England, United Kingdom