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A randomised controlled trial of the effect of exercise training on exercise capacity in older patients with heart failure

A randomised controlled trial of the effect of exercise training on exercise capacity in older patients with heart failure

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN51615566
Enrollment
112
Registered
2007-07-03
Start date
2007-08-06
Completion date
Unknown
Last updated
2018-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic heart failure Circulatory System Chronic heart failure

Interventions

Intervention group: Eight weeks of twice per week therapist-led supervised small group intermittent functional aerobic exercise and strength training, with the duration of sessions gradually increased

Sponsors

University of Dundee (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients will be recruited from day hospital, heart failure and cardiology clinics 1. Patients aged 70 years or older 2. Diagnosis of chronic heart failure according to the European Society of Cardiology guidelines 3. Evidence of Left Ventricular (LV) systolic dysfunction 4. In the New York Heart Association class II or III

Exclusion criteria

Exclusion criteria: 1. Aortic stenosis with peak gradient >30 mmHg 2. Sustained Ventricular Tachycardia (VT) or Ventricular Fibrillation (VF) outside of the context of an acute myocardial infarction 3. Unstable angina 4. Unable to walk without human assistance 5. Atrial fibrilation with a ventricular rate of >100/min 6. Currently enrolled in another trial

Design outcomes

Secondary

MeasureTime frame
The following will be recorded at baseline, 8 and 24 weeks: 1. Change in quadriceps muscle strength 2. Repetitive strength 3. Incremental shuttle walk test 4. Quality of life 5. Carer strain 6. Mood and self reported function

Primary

MeasureTime frame
Change in 6 minute walking distance, recorded at baseline, 8 and 24 weeks

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 27, 2026