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Comparison of the post-operative pain relief provided by the administration of either a femoral nerve block or fascia iliaca compartment block at one of two different doses in patients undergoing surgery for hip fracture

Comparison of fascia iliaca compartment block or femoral nerve block using levobupivacaine for post-operative analgesia after operative repair of femoral neck fracture - dose response study: a randomised controlled double-blind trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN51569968
Enrollment
120
Registered
2009-10-01
Start date
2009-08-31
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fractured neck of femur Injury, Occupational Diseases, Poisoning Fracture of femur

Interventions

Patients will be randomised to four groups - all blocks will be performed under ultrasound guidance: Group I: Fascia iliaca compartment block at a dose of 1 mg/kg levobupivacaine Group II: Fascia ilia

Sponsors

Belfast Health and Social Care Trust (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. American Society of Anaesthesiologists (ASA) class I - III 2. Patients able to give written informed consent 3. Patients requiring operative repair of fractured neck of femur 4. Patients aged 18 years and over, either sex

Exclusion criteria

Exclusion criteria: 1. History of allergy to any of the medications used in the study 2. Patients with a history of dementia or difficulty in providing informed consent 3. Patients with a history of significant neurological impairment of one or both of the lower limbs 4. Patients with a pathological fracture of the neck of femur 5. Patients suffering from severe hypotension such as cardiogenic or hypovolaemic shock or with a serious cardiac arrhythmia

Design outcomes

Primary

MeasureTime frame
Comparison of post-operative pain scores after one of two nerve blocks using one of two doses of the local anaesthetic following operative repair of fractured neck of femur. A post-operative assessment will be performed in the recovery room and at 4, 24 and 48 hours post-procedure. Pain scores will also be recorded by nursing staff whilst assessing routine observations.

Secondary

MeasureTime frame
Assessed at 4, 24 and 48 hours post-operatively: 1. Incidence of motor blockade 2. Post-operative analgesia requirements and time to first request of post-operative analgesia 3. Ability to mobilise on the first post-operative day 4. Incidence of any adverse events 5. One and three month mortality

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026