Topic: Dermatology
Conditions
Interventions
Patients will be given written information about the study and asked to give informed consent to participate. Patients will be given at least 48 hours to decide if they wish to participate. If they ag
weekly PASI scores will be recorded throughout treatment to assess their progress. After 15 treatments, patients still receiving treatment will be randomised to receive targeted narrowband UVB (308 Ex
Sponsors
Newcastle upon Tyne Hospitals NHS Foundation Trust (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age of 18 years or older 2. Gives written informed consent to the study 3. Has chronic plaque psoriasis and has been routinely prescribed narrowband UVB
Exclusion criteria
Exclusion criteria: 1. Pregnancy 2. Patients on systemic treatment for psoriasis within the past 3 months 3. Patients with significant UV exposure over the past 1 month (sunny holidays /sunbeds etc) 4. Patients with a previous history of malignant skin cancer 5. Non-English speaking patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of remission achieved in psoriasis patients following a course of Narrowband UVB (NbUVB) ismeasured through monthly telephone calls after completion of treatment until study end. Patients are recalled and undergo a skin evaluation if psoriasis has flared.When >50% of the original PASI score is reached, the patients involvement in the study is complete. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Duration of remission achieved in patients who achieve “complete” clearance of psoriasis versus those who achieve “almost complete” clearance. Complete clearance was defined as 100%, and almost complete as 75-99% clear. 2. Practicality and effectiveness of the 308nm Excimer lamp in clearing more ‘resistant’ plaques alongside a standard course of NbUVB by nurse questionnaire | — |
Countries
United Kingdom
Outcome results
None listed