Topic: Primary Care Research Network for England
Conditions
Interventions
Patients will be approached by either advertising in the practice, when seeing their doctor/nurse (who will provide information to the patient with the consent form) or by writing to patients with kno
Sponsors
University of Southampton (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Presenting with acute sore throat 2. Over the age of 16 years, either sex
Exclusion criteria
Exclusion criteria: 1. History suggestive of quinsy 2. Previous rheumatic fever, glomerulonephritis 3. Phenylketonuria 4. Allergy to xylitol, sorbitol or probiotics 5. Patients unwilling or unable to self medicate with gum or probiotics for the duration of the study or complete outcome measures 6. Subjects with serious chronic disorders where antibiotics are automatically needed (e.g. cystic fibrosis) 7. Suspected pregnancy 8. Immune deficiency
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The mean score for sore throat and difficulty swallowing during 2 - 5 days after presentation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Time to resolution of sore throat 2. Time taken off work or unable to do normal activities 3. Satisfaction with treatment | — |
Countries
United Kingdom
Outcome results
None listed