Ear, Nose and Throat: Smell ability Ear, Nose and Throat Smell ability
Conditions
Interventions
Current interventions as of 19/02/2013:
The study will be undertaken at the ENT department of the Leicester Royal Infirmary and in a research laboratory at the University of Leicester and also in the
Sponsors
University Hospitals of Leicester NHS Trust (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All patients with an objective reduction in their ability to smell.
Exclusion criteria
Exclusion criteria: Current inclusion criteria as of 19/02/2013: 1. Patients who are proven to have a normal sense of smell 2. Patients with nasal polyps or other sinonasal disease Previous inclusion criteria until 19/02/2013: 1. Patients who are proven to have a normal sense of smell 2. Patients with nasal polyps
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome measure as 29/07/2016: Olfactory threshold for PEA odour is measured using a psychophysical test (two-alternative forced choice ascending ladder technique) at baseline and 15 minute intervals up to 2 hours maximum. Original primary outcome measure: An improvement in their sense of smell and their general well-being. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measure as of 29/07/2016: Olfactory thresholds for ACA, EUC and BUT odours are measured using a psychophysical test (two-alternative forced choice ascending ladder technique) at baseline and 15 minute intervals up to 2 hours maximum. Secondary outcome measures added as of 19/02/2013: A subjective improvement in their sense of smell and their general well-being | — |
Countries
United Kingdom
Outcome results
None listed