Skip to content

Application of Multiple Cerebral Monitoring Severe Traumatic Brain Injury: a multicentre study

Application of Multiple Cerebral Monitoring Severe Traumatic Brain Injury: a multicentre study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN50689988
Enrollment
320
Registered
2007-07-10
Start date
2006-09-01
Completion date
Unknown
Last updated
2021-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe Traumatic Brain Injury Nervous System Diseases Severe Traumatic Brain Injury

Interventions

The hospitals included in this series were Wan Fang Hospital, Veterans General Hospital, Taipei, National Taiwan University Hospital, Mackay Memorial Hospital, Shin Kong Wu Ho-Su Memorial Hospital and

Sponsors

Department of Health, Taipei City Government (Taiwan)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Glasgow Coma Scale (GCS) score three to eight will be enrolled in this study.

Exclusion criteria

Exclusion criteria: 1. Patients manifesting severe systemic injury with hypotension (systolic blood pressure less than 90 mmHg on admission) 2. GCS score three with fixed and dilated pupils after resuscitation 3. GCS score three to four with family refused aggressive treatment 4. Patients transferred from another institution longer than 24 hours after injury 5. Those who were dead on arrival

Design outcomes

Primary

MeasureTime frame
1. Application of multiple cerebral blood monitor in the treatment of STBI could result in reduced mortality rate and impaired quality of life 2. Patients with impaired autoregulation, the optimal CPP value could be changed

Secondary

MeasureTime frame
1.Through this study, the result could be contributed to the establishment of a new Clinical Practice Guideline of STBI 2. The result could be used as a guideline to train young physicians 3. In different groups, patients with multiple cerebral monitoring will have better GOS, GOSE, HRQL, and survival

Countries

Taiwan

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026