Topic: Stroke Research Network
Conditions
Interventions
Participants will be into one of two treatment groups using a computer generated randomization list 1:1 into one of both groups with stratification for baseline treadmill speed to balance groups for w
Sponsors
Oxford Brookes University (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Adults will be selected who are more than 6 months following a first stroke with some walking impairment. Walking impairment will be determined by asking participants, on initial expression of interest to participate, if they have a walking problem (Yes/No) and confirmed by a reduced six minute walk distance (compared to normative data) on testing 2. With an ischaemic infarct 3. Able to perform a simple reciprocal bilateral foot tapping task 4. Walk safely on a treadmill with or without mobility aids and to give informed consent.
Exclusion criteria
Exclusion criteria: 1. Individuals with a high risk of psychosis 2. Aphasia significantly limiting communication 3. History of previous symptomatic stroke or neurological disease 4. A mental state that precludes safe participation (as stated by GP or referring consultant) 5. Any known contraindication to safe participation in exercise. 6. Individuals will be checked for safe participation in the MRI scanning: claustrophobia, or other conditions precluding safe MRI (e.g., pacemaker or other metal implant). Individuals determined safe and willing to take part will participate in additional scanning.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcomes as of 16/01/2017: 1. Walking performance is measured using the Two minute walk test at baseline, 11, 22 weeks 2. Walking performance in dual task conditions is measured using the Two minute walk test with distraction at 0, 11, 22 weeks 3. Community walking ability and confidence about community walking is measured using Community walking questions at at 0, 11, 22 weeks Original primary outcome: Effect of walking whilst performing distracting tasks training | — |
Secondary
| Measure | Time frame |
|---|---|
| Added 16/01/2017: 1. Dual task effect on walking distance during two minute walk with distraction is measured by the change in walking distance from single to dual task at baseline, 11, 22 weeks 2. Number of cognitive responses during two minute walk with distraction is measured by cognitive response rate walking at baseline, 11, 22 weeks 3. Physical activity level is measured using the Physical activity scale for elderly at baseline, 11, 22 weeks 4. Physical activity and community walking levels are measured using Step activity monitors, worn for a week at baseline, 11, 22 weeks 5. General health and wellbeing are measured using the SF-36 questionnaire at baseline, 11, 22 weeks 6. Health and wellbeing on the day is measured using the EQ-5D questionnaire at baseline, 11, 22 weeks 7. Community walking levels specified for specific surroundings is measured using the Modified version of the University of Alabama study of Aging Life Space Assessment at baseline, 11, 22 weeks | — |
Countries
United Kingdom
Outcome results
None listed