The effects of upper-limb aerobic exercise training on walking performance and lower limb circulatory function in patients with peripheral arterial disease

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN50394448

Enrollment

Registered

2006-09-27

Start date

2006-09-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peripheral arterial disease (intermittent claudication) Circulatory System Peripheral arterial disease (intermittent claudication)

Interventions

Upper-limb aerobic exercise intervention (arm-cranking exercise training, twice per week for 12 weeks) versus usual patient care.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Symptoms of intermittent claudication for at least 12 months 2. Ankle Brachial Pressure Index (ABPI) more than 0.9 3. No interventional procedure in last 12 months 4. Ability to undertake exercise 5. No exercise-limiting angina 6. No shortness of breath 7. No severe arthritis

Exclusion criteria

Exclusion criteria: 1. Experiencing symptoms of intermittent claudication for less than 12 months 2. Reporting a significant change in walking ability during previous 12 months, denoting unstable claudication 3. Exhibiting features of critical limb ischaemia 4. Re-vascularisation procedure or other surgical intervention to the lower limbs in the previous 12 months 5. Severe arthritis 6. Unstable cardiopulmonary conditions such as shortness of breath or exercise-limiting angina

Design outcomes

Primary

Measure	Time frame
Walking performance.	—

Secondary

Measure	Time frame
Changes in lower-limb circulatory function.	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026