Diabetes mellitus and nephropathy Nutritional, Metabolic, Endocrine Diabetes mellitus
Conditions
Interventions
We compared the effects of a Normal Protein Diet (NPD) (1.38 ± 0.08 g/kg/day) or a Low Protein Diet (LPD) (0.81 ± 0.04 g/kg/day) on Endogenous Leucine Flux (ELF), albumin and fibrinogen synthesis (5,5
Sponsors
Second University of Naples (Seconda Universita degli studi di Napoli) (Italy)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Eligibility criteria of type 2 diabetic patients included: 1. Body Mass Index (BMI) less than 35 kg/m^2 2. Proteinuria greater than 3 g/day 3. Absence of urinary tract infection or other renal diseases Age range and gender of our participants are: 1. DM2 (60 ± 2 years): 6 males, 3 females 2. Control (37 ± 3 years): 3 males and 3 females
Exclusion criteria
Exclusion criteria: Exclusion criteria of type 2 diabetic patients included: 1. BMI greater than 35 kg/m^2 2. Proteinuria less than 3 g/day
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Albumin and fibrinogen synthesis, measured at baseline and four weeks pre-LPD and post-LPD. | — |
Secondary
| Measure | Time frame |
|---|---|
| Proteinuria and low-grade inflammation, measured at baseline and four weeks pre-LPD and post-LPD. | — |
Countries
Italy
Outcome results
None listed