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Effects of exercise training on obstructive and central sleep apnea in coronary artery disease

Effects of exercise training on obstructive and central sleep apnea in coronary artery disease: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN50108373
Enrollment
44
Registered
2014-09-23
Start date
2014-09-17
Completion date
Unknown
Last updated
2020-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease patients with obstructive or central sleep apnea Circulatory System

Interventions

The intervention consists of an exercise training program including 20 sessions over a 4-week period. Each exercise session will begin with a 10 minute warm-up followed by 30 minutes of moderate-inten

Sponsors

Canadian Institutes of Health Research
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Men and women 18-80 yrs of age with coronary artery disease (defined as a documented myocardial infarction, coronary bypass surgery or coronary angioplasty and/or stenting) and obstructive or central sleep apnea (AHI greater than 15 events/hr)

Exclusion criteria

Exclusion criteria: 1. Angina 2. Use of diuretics 3. Adeno-tonsillar hypertrophy 4. Inability to walk due to orthopedic or musculoskeletal problems 5. Previously treated OSA 6. Patients exercising more than 150 minutes per week at moderate intensity

Design outcomes

Primary

MeasureTime frame
Apnea hypopnea index, measured by polysomnogram at baseline and 4-weeks

Secondary

MeasureTime frame
1. Leg fluid volume measured by bio-electrical impendence 2. Overnight changes in leg fluid volume, thoracic fluid volume, neck circumference and neck fluid volume measured by bio-electrical impendence 3. Upper-airway cross-sectional area measured by acoustic pharyngometry

Countries

Canada

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 19, 2026