Cystic fibrosis Nutritional, Metabolic, Endocrine Cystic fibrosis
Conditions
Interventions
Participants will complete two daily voice recordings on the Sonde app using a personal smartphone. Each daily voice sample will take approximately 1 minute to complete a 6-second held vowel “ahhh.” P
Sponsors
Royal Papworth NHS Foundation Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Diagnosis of cystic fibrosis based on genetic testing and/or sweat chloride levels 2. Age between >/= 18 to </= 65 years of age at time of consent 3. Able to provide written informed consent 4. Patients who are currently undertaking home monitoring/virtual clinics 5. Patients who have the use of a smartphone
Exclusion criteria
Exclusion criteria: 1. Patients unable to provide written informed consent 2. Patients who are currently not undertaking home monitoring/virtual clinics 3. Lung transplant recipients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The accuracy of the Sonde predictive algorithm to predict when antibiotics will be required to treat an acute pulmonary exacerbation. This will be from the sensitivity and specificity of the predictive algorithm when compared to the Project Breathe predictive algorithm over a 12-month period. | — |
Secondary
| Measure | Time frame |
|---|---|
| The accuracy of the Sonde predictive algorithm to substitute for spirometry and pulse oximetry. This will be from the sensitivity and specificity of the Sonde predictive algorithm when compared to spirometry and pulse oximetry over a 12-month period. | — |
Countries
England, United Kingdom
Contacts
Public ContactLucy Gale
Outcome results
None listed