To compare analgesia and side effects of intrathecal fentanyl and intrathecal morphine

A randomised controlled trial to compare analgesia and side effects of intrathecal fentanyl and intrathecal morphine

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN49793641

Enrollment

Registered

2009-03-27

Start date

2009-05-01

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Analgesia and anaesthesia in orthopaedic surgery Musculoskeletal Diseases Analgesia and anaesthesia in orthopaedic surgery

Interventions

The 90 patients will be randomised into 3 groups. The first group will be given 2.5 ml of heavy bupivacaine 0.5% with 25 mcg of fentanyl intrathecally, the second group will be given 2.5 ml of heavy b

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Both males and females, aged 18-100 2. American Society of Anesthesiologists (ASA) 1 and 2 3. Patients planned for an elective orthopaedic surgery needing spinal anaesthetic as part of routine anaesthetic management

Exclusion criteria

Exclusion criteria: 1. Children <18 years old 2. Pregnant women 3. Patients with contraindications to spinal anaesthetic 4. Patients unable to give informed consent

Design outcomes

Primary

Measure	Time frame
Analgesic usage in first 24 hours.	—

Secondary

Measure	Time frame
The following will be monitored for the first 24 hours: 1. Vasopressors usage 2. Blood pressure (BP) 3. Respiratory rates 4. Side effects	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026