Colorectal Cancer Cancer Colorectal Cancer
Conditions
Interventions
All participants recruited in the study are asked to complete a stool sample, and return it to the laboratory for FIT analysis. The faecal haemoglobin level are compared to the findings from the colon
Sponsors
Croydon Health Services NHS Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. All patients referred under the 2WW urgent referral system and triaged for a colonoscopy examination 2. 18 years of age or older 3. Willing to provide informed consent
Exclusion criteria
Exclusion criteria: 1. Unable to undergo colonoscopy 2. Unable to take adequate stool sample (including those taken during bowel preparation) 3. Unable to give an informed consent due to lack of capacity 4. Unable to give informed consent because of language barrier, when a relative over 18 is unable to translate, a staff member who speaks the same language cannot be found, or online translation service are unsuccessful
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Identify a suitable cut-off for the test 2. Calculate the sensitivity of the test using the chosen cut-off for colorectal polyps | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Calculate the specificity, negative- and positive-predictive values for the chosen cutoff 2. Explore the effects of other prognostic factors on the sensitivity and the suitability of the cut-off value: 2.1. Cancer site 2.2. Site and size of adenomas 3. Assessing the levels of FHb in benign non-neoplastic pathology The above data will be collected from reviewing patient notes and correlated with the faecal haemoglobin detected by the lab. | — |
Countries
England, United Kingdom
Outcome results
None listed