Kinetic Oscillation Stimulation (KOS) in chronic hemodialysis: new potential anti-inflammatory treatment

Modulation of the Cholinergic Anti-inflammatory Pathway in DIAlysis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN49663124

Enrollment

Registered

2014-12-04

Start date

2014-11-24

Completion date

Unknown

Last updated

2015-07-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic inflammation in chronic dialysis patients Urological and Genital Diseases

Interventions

We will use the Kinetic Oscillation Stimulation (KOS) device in chronic hemodialysis 3 times weekly during 10-15 minutes prior to the dialysis session. The device is inserted into one of the nostrils

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All stable adult patients with no age limit undergoing chronic dialysis.

Exclusion criteria

Exclusion criteria: Ongoing clinical infection.

Design outcomes

Primary

Measure	Time frame
1. Inflammatory markers in serum and in stimulated whole blood during follow-up compared to prior to stimulation. 2. Heart rate variability by EKG ( autonomic dysfunction assessment) during follow-up compared to prior to stimulation	—

Secondary

Measure	Time frame
Health assessment questionnaires	—

Countries

Sweden

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026