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Intra-articular injection of fat micro graft: simple treatment for knee osteoarthritis with local injection of patient own fat

Intra-articular Injection of autologous fat graft for the treatment of knee osteoarthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN49625613
Enrollment
80
Registered
2016-05-11
Start date
2011-12-20
Completion date
Unknown
Last updated
2018-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis Musculoskeletal Diseases

Interventions

Patients are told what the treatment involves and are asked to give consent. The treatment involves using the self-lubricating effect of their own fat (autologous fat) inside the joint to improve join

Sponsors

King Abdulaziz University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Adults with severe to moderate knee osteoarthritis changes, confirmed by bilateral anterior - posterior standing and lateral supine radiographs involving one or both knees

Exclusion criteria

Exclusion criteria: 1. Recent knee surgery 2. Chronic opoid intake 3. Bleeding disorders 4. Malignant disease 5. A congenital or traumatic deformity of the knee joint 6. Refusal of the patient to be included

Design outcomes

Primary

MeasureTime frame
Improvement in the pain and stiffness of the joint physical function by the combined lubricating and regenerative effect of fluid preparation. This is measured by pain experienced at rest and during activity using the visual analogue score (VAS) at preoperative visit and postoperative visit.

Secondary

MeasureTime frame
1. Joint physical function, measured using the Western Ontario and McMaster Universities Osteoarthritis Index at 3 months after surgery 2. Extent of repair of the osteoarthritic joint as indicated by arthroscopy of the fat injected joint (a minimally invasive surgical procedure to examine the damage of the joint) at 3 months after surgery

Countries

Saudi Arabia

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026