FindTrial
Sign In

A study of the effect of transcranial magnetic stimulation on cerebellum vermis in treatment-resistant schizophrenia

Efficacy of adjunctive intermittent theta-burst transcranial magnetic stimulation for treatment-resistant schizophrenia: a randomized placebo-controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN49569866
Enrollment
40
Registered
2020-06-08
Start date
2019-05-15
Completion date
Unknown
Last updated
2022-03-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Treatment-resistant schizophrenia Mental and Behavioural Disorders Schizophrenia

Interventions

Participants will be randomized using a lottery method to receive either the intervention of intermittent theta burst transcranial magnetic stimulation to the cerebellar vermis or placebo control.

Sponsors

Shri Guru Ram Rai Institute
Lead Sponsor
Shri Mehent Indiresh Hospital
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Diagnosis of schizophrenia, according to ICD-10 criteria 2. Treatment-resistant schizophrenia, according to Modified Kane Criteria. 3. Right-handed 4. Normotensive 5. Aged 18 to 59 years

Exclusion criteria

Exclusion criteria: 1. Neurological disorders with a history of epilepsy, organ damage, and any neurological procedure 2. Pacemakers or other implanted metal devices 3. Received ECT =6 months before enrolment 4. Substance use disorders, except nicotine and caffeine

Design outcomes

Primary

MeasureTime frame
Schizophrenia symptoms measured using the Positive And Negative Symptoms Scale rating done at 0, 7, 21 days—

Secondary

MeasureTime frame
Schizophrenia symptoms measured using the following at 0, 7, 21 days: 1. Simpson-Angus Extrapyramidal Side-Effects Scale (SAS) 2. Schizophrenia Cognition Rating Scale (SCoRS) 3. Brief Psychiatric Rating Scale (BPRS) 4. Clinical Global Impression (CGI) scale—

Countries

India

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026