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Aetiology of preoperative anaemia in cardiac surgery

A prospective observational study to investigate the aetiology of preoperative anaemia in patients undergoing elective cardiac surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN49461366
Enrollment
200
Registered
2012-01-23
Start date
2012-01-01
Completion date
Unknown
Last updated
2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preoperative anaemia Haematological Disorders

Interventions

Standard preoperative blood test results will be noted. Additional blood will be taken for further tests. This forms the initial workup to determine the different causes of anaemia. Intraoperatively a

Sponsors

Papworth Hospital (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Consecutive patients, 18 years or older, scheduled to undergo elective cardiac surgery requiring cardiopulmonary bypass, who are anaemic at preoperative testing 2. Patients requiring: 2.1. First time or redo sternotomy 2.2. Coronary artery bypass grafting 2.3. Valve replacement or repair 2.4. Operation on the aorta

Exclusion criteria

Exclusion criteria: 1. Hb = 13 g/dL in men and = 12 g/dL in women at preoperative testing 2. Emergency (non-scheduled) surgery

Design outcomes

Primary

MeasureTime frame
To investigate the aetiology of preoperative anaemia, as defined by the WHO criteria, in adult patients undergoing scheduled cardiac surgery.

Secondary

MeasureTime frame
1. To gain information on the relative frequency and prognostic implications of the different types of preoperative anaemia 2. To assess the validity of the blood based tests in distinguishing the different types of preoperative anaemia 3. To devise a diagnostic algorithm and therapeutic regimes required for assessing and correcting anaemia before cardiac surgery takes place

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026