Transcranial doppler sonography with a transorbital approach as a confirmatory test in the diagnosis of brain death

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN49093383

Enrollment

Registered

2008-10-27

Start date

2005-10-01

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain death Nervous System Diseases Other disorders of brain

Interventions

All patients underwent cerebral angiography, transcranial doppler examination of the basilar, anterior and middle cerebral arteries bilaterally. In addition, the patients in the intervention group wer

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Brain dead patients of the intensive care unit (both males and females, aged greater than 16 years) who were hospitalised from October 2005 to July 2008.

Exclusion criteria

Exclusion criteria: 1. Patients with an episode of hypoxia or hypotension during the angiographic or transcranial doppler examinations 2. Patients with no flow at the initial transcranial doppler examination in any approach

Design outcomes

Primary

Measure	Time frame
Blood flow patterns measured by transcranial doppler sonography with a suboccipital, transtemporal and transorbital approach.	—

Secondary

Measure	Time frame
Efficacy of the transorbital approach in the diagnosis of brain death with transcranial doppler sonography.	—

Countries

Greece

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026