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Comparison of different techniques regarding visualization of scars in the heart muscle using cardiac MRI

Comparison of fast multi-slice and standard segmented techniques for detection of late gadolinium enhancement in ischemic and non-ischemic cardiomyopathy - a prospective clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN48802295
Enrollment
302
Registered
2017-07-10
Start date
2014-11-01
Completion date
Unknown
Last updated
2019-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myocardial infarction, hypertrophic cardiomyopathy and inflammatory heart disease Circulatory System

Interventions

This is an observational study in which three different techniques are compared for visualization of myocardial fibrosis using late Gadolinium enhancement in patients with known or suspected cardiomyo

Sponsors

Charité University Medicine Berlin
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Known or suspected chronic myocardial infarction, hypertrophic cardiomyopathy or inflammatory heart disease 2. Clinical indication for MR exam with late gadolinium enhancement 3. Age range =18 years (no upper limit)

Exclusion criteria

Exclusion criteria: 1. Any contraindication for MR exam 2. Acute or chronic renal failure with GFR <30ml/min

Design outcomes

Primary

MeasureTime frame
Size of myocardium with late Gadolinium enhancement in each tested MR sequence, measured by semiautomated threshold method in MRI DICOM data at one timepoint, the date of the MRI (no follow up)

Secondary

MeasureTime frame
1. Contrast-to-noise ratio in each tested MR sequence, measured using MRI DICOM data 2. Image quality, scored on a 4-point-scaling system based on visual assessment by blinded readers Measured at at one timepoint, the date of the MRI (no follow up)

Countries

Germany

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 7, 2026