Fractured proximal femurs Musculoskeletal Diseases Fractured proximal femurs
Conditions
Interventions
Local anaesthetic blockade of the femoral nerve (0.5% bupivacaine) versus placebo (0.9% sterile saline) in patients with fractured proximal femurs.
Sponsors
South Devon Healthcare NHS Trust (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged over 18 years 2. Fractured proximal femur 3. Capable of informed consent 4. Written informed consent obtained
Exclusion criteria
Exclusion criteria: 1. Documented allergy to bupivacaine 2. Infection at the site of catheter placement 3. Aged under 18 years 4. Unable to give informed consent 5. Refusal to give informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the quality of anaesthesia provided by systemic opioids alone or combined with femoral nerve blockade in two otherwise equivalent groups by measuring pain scores and levels of systemic opioid administration required. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To assess mental function using a standard ten point scale (Abbreviated Mental Test Score [AMTS]) and a 30 point scale (Mini Mental State Examination [MMSE]) before and after the operation, comparing the two groups 2. To assess mobility and function, using a modified Physiotherapy Functional Mobility Profile (PFMP) and achievement of activities for daily living score (MIMS), before and after the operation, comparing the two groups 3. To monitor the lengths of stay in the two groups 4. To monitor the incidence of death in the two groups at 30 days and 90 days 5. To monitor the levels and incidence of infections to the wound, prosthesis and/or catheter post operatively | — |
Countries
United Kingdom
Outcome results
None listed