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Treament of impaired sperm quality with micronutrients

Comparison of the effect of a combination of eight micronutrients versus a standard mono preparation on sperm parameters

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN48594239
Enrollment
280
Registered
2016-10-07
Start date
2004-01-11
Completion date
Unknown
Last updated
2017-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Reduced reproductive capability in men presenting an unexplained (unidentified) abnormal semen analysis Urological and Genital Diseases

Interventions

A total of 299 participants who met the inclusion criteria were invited to participate. Participant number 1 was allocated to group 1, participant number 2 to group 2, participant number 3 to group 1
Profertil®, Lenus Pharma GmbH, Vienna, Austria) Semen analysis was performed at baseline and after three months of treatment.

Sponsors

Karl Landsteiner Institute of Cell-Based Treatment in Gynecology (Karl Landsteiner Institut für zellorientierte Therapie in der Gynäkologie)
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1. Male 2. 20 to 60 years of age 3. Suffering from at least one year of subfertility 4. At least one recent pathological semen analysis result

Exclusion criteria

Exclusion criteria: 1. Azoospermia 2. Aspermia 3. Varicocele 4. Recent urogenital infections 5. Hormonal disorders.

Design outcomes

Primary

MeasureTime frame
The following sperm parameters were analysed at baseline and after 3 months of treatment: 1. Sperm volume (ml) 2. Sperm density (mio/ml) 3. Overall, fast and slow progressive motility (expressed as %) 4. % of sperm with normal morphology All parameters were defined according to WHO guidelines (4th edition). Sperm analysis was performed with an automatic, computer analysing system called Sperm Class Analyzer® CASA System, by MICROPTIC SL, company based in Barcelona, Spain.

Countries

Austria

Contacts

Public ContactMarkus Lipovac

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 28, 2026