Pediatric asthma exacerbation Respiratory Asthma
Conditions
Interventions
Children 2 to 18 years with previously diagnosed asthma with moderate to severe asthma exacerbation (asthma score > 5) were randomized to high concentration oxygen therapy (100% oxygen via face mask a
Sponsors
Pediatric Critical Care Department
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients between 2 to 18 years with previous medical diagnosis of asthma presenting with moderate to severe asthma exacerbation with asthma score > 5
Exclusion criteria
Exclusion criteria: 1. Disorders with hypercapnic respiratory failure such as neuromuscular disease, chest wall restriction, or obesity hypoventilation 2. Unconscious patient 3. Pregnancy 4. Receiving sedatives/depressants 5. History of congenital heart disease 6. Disease of cardiac, renal, or hepatic systems 7. History of smoking
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rise in transcutaneous carbon dioxide, measured via a transcutaneous carbon dioxide monitor at 0, 20, 40, 60 minutes and then every 30 minutes till disposition decision was reached by the ED physician | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Change of > 4 mmHg PtCO2 and > 38 mmHg PtCO2 measured via a transcutaneous Co2 monitor at 0, 20, 40, 60 minutes and then every 30 minutes till disposition decision was reached by the ED physician 2. Change in asthma score, measured via a validated respiratory score tool used by the hospital as part of the asthma treatment pathway at 0, 20, 40, 60 minutes and then every 30 minutes till disposition decision was reached by the ED physician 3. Admission rates | — |
Countries
United States of America
Contacts
Public ContactBhavi Patel
Outcome results
None listed