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Stroke despite treatment with blood thinners: causes and outcomes

Ischemic stroke despite anticoagulant therapy in patients with atrial fibrillation - causes, subsequent treatment strategies and outcomes

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN48292829
Enrollment
2000
Registered
2021-07-23
Start date
2012-01-01
Completion date
Unknown
Last updated
2022-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic stroke despite oral anticoagulation in patients with atrial fibrillation Circulatory System

Interventions

This retrospective observational study will determine the most probable cause of stroke according to one of the following categories: (a) competing stroke etiology other than atrial fi
(b) medication error or (c) treatment failure (neither (a) nor (b)). The study will examine the characteristics of patients stratified to these categories, as well as the subsequent p

Sponsors

University Hospital of Bern
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients presenting with imaging proven ischemic stroke who had nonvalvular atrial fibrillation known before stroke onset and were on oral anticoagulant treatment at stroke onset

Exclusion criteria

Exclusion criteria: Patients with mechanical heart valves and those without information on anticoagulant treatment at stroke onset

Design outcomes

Primary

MeasureTime frame
Measured using patient records: 1. Recurrent ischemic stroke at 3 months 2. Intracranial hemorrhage at 3 months 3. All-cause death at 3 months

Secondary

MeasureTime frame
There are no secondary outcome measures

Countries

Germany, Switzerland, United States of America

Contacts

Public ContactAlexandros Polymeris
alexandros.polymeris@usb.ch+41 61 328 73 19

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 12, 2026