Cost-effectiveness of nutritional supplementation and exercise programme among older people in Santiago, Chile

Conditions

Pneumonia and physical functional decline Respiratory Pneumonia and functional ability

Keith M. Godfrey, Philip Titcombe, Sarah El‐Heis, Benjamin B. Albert, Elizabeth Huiwen Tham et al. (13 authors)

PLoS Medicine2023-12-0520 citations

10.1371/journal.pmed.1004260

Adherence to a physical activity intervention among older adults in a post-transitional middle income country: a quantitative and qualitative analysis.

Garmendia ML, Dangour AD, Albala C, Eguiguren P, Allen E, Uauy R.

2013-01-0128 citations

10.1007/s12603-012-0417-1

Methods for economic evaluation of a factorial-design cluster randomised controlled trial of a nutrition supplement and an exercise programme among healthy older people living in Santiago, Chile: the CENEX study.

Walker DG, Aedo C, Albala C, Allen E, Dangour AD, Elbourne D, Grundy E, Uauy R.

2009-05-2712 citations

10.1186/1472-6963-9-85

A factorial-design cluster randomised controlled trial investigating the cost-effectiveness of a nutrition supplement and an exercise programme on pneumonia incidence, walking capacity and body mass index in older people living in Santiago, Chile: the CENEX study protocol.

Dangour AD, Albala C, Aedo C, Elbourne D, Grundy E, Walker D, Uauy R.

2007-07-0515 citations

10.1186/1475-2891-6-14

Interventions

The study has been designed as a full-factorial cluster-randomised trial. There will be 28 clusters which are defined as health centre catchment areas, and 100 individuals will be randomly selected f

the remaining eight clusters will be randomly assigned to either the nutritional supplement or the control arm. The four study interventions are: 1. Provision at the local health centre of monthly sup

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 65.0 to 67.9 at baseline 2. Living in the catchment area of one of 28 selected health centres of low/medium socio-economic status in Santiago, Chile

Exclusion criteria

Exclusion criteria: 1. Non-ambulatory 2. Recent un-explained weight loss (more than 3 kg in past three months) 3. Possible clinical dementia (as assessed via mini-mental state examination)

Design outcomes

Primary

Measure	Time frame
Current information as of 22/09/2010: 1. For nutrition intervention: The incidence of pneumonia over the 24 months after the initiation of the intervention. 2. For exercise intervention: Walking capacity (distance walked in six minutes) 24 months after initiation of the intervention. Initial information at time of registration: 1. Incidence of pneumonia over 24 months of intervention and subsequent six months 2. Change in walking capacity over 24 months of intervention 3. Change in body mass index over 24 months of intervention	—

Measure

Time frame

Current information as of 22/09/2010: 1. For nutrition intervention: The incidence of pneumonia over the 24 months after the initiation of the intervention. 2. For exercise intervention: Walking capacity (distance walked in six minutes) 24 months after initiation of the intervention. Initial information at time of registration: 1. Incidence of pneumonia over 24 months of intervention and subsequent six months 2. Change in walking capacity over 24 months of intervention 3. Change in body mass index over 24 months of intervention

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Secondary

Measure	Time frame
Added 22/09/2010 1. Body mass index 2. Incidence of acute respiratory infection 3. Self-reported health status (Short-Form 36) 4. Depression, assessed bt Geriatric Depression Scale (GDS-15) 5. Self-reported incidence of chronic diseases 6. Physical and functional limitations 7. Self reported productive activity 8. Self-reported incidence of falls 9. Self-reported incidence of fracture 10. Blood pressure 11. Anthropometry 12. Timed up-and-go assessment 13. Blood indicators of cardiovascular disease risk and insulin resistance (in a sub-sample)	—

Measure

Time frame

Added 22/09/2010 1. Body mass index 2. Incidence of acute respiratory infection 3. Self-reported health status (Short-Form 36) 4. Depression, assessed bt Geriatric Depression Scale (GDS-15) 5. Self-reported incidence of chronic diseases 6. Physical and functional limitations 7. Self reported productive activity 8. Self-reported incidence of falls 9. Self-reported incidence of fracture 10. Blood pressure 11. Anthropometry 12. Timed up-and-go assessment 13. Blood indicators of cardiovascular disease risk and insulin resistance (in a sub-sample)

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Countries

Chile

Outcome results

None listed