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PRODIGY: Prevention of long-term social disability amongst young people with emerging psychological difficulties

PRODIGY: Prevention of long-term social disability amongst young people with emerging psychological difficulties - a definitive randomised controlled trial of social recovery cognitive behavioural therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN47998710
Enrollment
270
Registered
2012-11-29
Start date
2013-02-01
Completion date
Unknown
Last updated
2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mental Health / Psychosis Mental and Behavioural Disorders Unspecified nonorganic psychosis

Interventions

1. Social Recovery focused Cognitive Behavioural Therapy 2. Standard care The intervention is Social Recovery oriented Cognitive Behavioural Therapy (SRCBT) and will b

Sponsors

Sussex Partnership NHS Foundation Trust
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Young people (male & female) aged 16 to 25 with severe and complex mental health problems showing early signs of persistent social disability 2. Presence of impairment in social and occupational functioning indicated by patterns of structured and constructive economic activity of less than 30 hours per week and a history of social impairment problems lasting for a period of longer than 6 months 3. Presence of severe and complex mental health problems defined operationally as: 3.1. Having attenuated psychotic symptoms which meet criteria for an At Risk Mental State; or 3.2. Having less severe attenuated psychotic symptoms but having severe and complex mental health problems which score at least 50 on the Global Assessment of Function Scale (which indicates the presence of severe symptoms of at least two of depression, anxiety, substance misuse, behavioural or thinking problems or subthreshold psychosis to the degree to impair function). 4. Also having a history of at least moderate symptoms persisting for longer than 6 months

Exclusion criteria

Exclusion criteria: 1. Age below 16 or above 25 2. Active positive psychotic symptoms or history of first episode psychosis 3. Severe learning disability (those with mild to moderate learning difficulties will not be excluded) 4. Organic neurological disorder 5. Unable to fully understand and answer standardised assessment questions or give informed consent due to insufficient English language proficiency

Design outcomes

Primary

MeasureTime frame
Current primary outcome measures: Time Use Survey (hours per week in structured activity) at 15 month follow-up Previous primary outcome measures: Time Use Survey (hours per week in structured activity) at baseline, post-intervention and 15 month follow-up

Secondary

MeasureTime frame
Current secondary outcome measures: Secondary outcomes include attenuated psychotic symptoms, anxiety, and depression (also assessed at baseline, 9 months, 15 months, and 24 months), in addition to time use at post-intervention (9 months) and 24 months, and intervention cost-effectiveness at 9 months, 15 months, and 24 months. Previous secondary outcome measures: Secondary outcomes include attenuated psychotic symptoms, anxiety, and depression. These are also assessed at baseline, 9 months, and 15 months.

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 19, 2026