Oral lichen planus Oral Health Lichen planus
Conditions
Interventions
This study will involve the review of participants charts with OLP diagnosed between January 1988 and December 2020 at one hospital in Northern Italy.
Sponsors
University of Turin
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Conclusive diagnosis of OLP based on the following criteria: 1. Clinical confirmation with the presence of characteristic bilateral clinical signs [papular and/or reticular lesions (Wickham striae) alone or in association with atrophic or erosive lesions], not related to oral amalgam restorations; 2. Histological confirmation, through incisional biopsy, demonstrating the following microscopic characteristic: 2.1. Presence of a well-defined band-like zone of cellular infiltration that is confined to the superficial part of the connective tissue, consisting mainly of lymphocytes 2.2. Signs of “liquefaction degeneration” in the basal cell layer 2.3. Lack of epithelial dysplasia
Exclusion criteria
Exclusion criteria: 1. Unable or unwilling to provide informed consent 2. Significant psychiatric or cognitive impairment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of the histopathological diagnosis of oral cancer in OLP patients measured using patient records at a single time point | — |
Secondary
| Measure | Time frame |
|---|---|
| Measured using patient records at a single time point: 1. The tumour site 2. T classification and neck nodes association 3. Treatment modalities 4. Outcome and survival rate | — |
Countries
Italy
Outcome results
None listed