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Effects of a short term Palaeolithic diet on fasting insulin, leptin and weight

Effects of a short term Palaeolithic diet on fasting leptin, insulin and weight in 41 healthy participants - an uncontrolled observational study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN47734717
Enrollment
41
Registered
2016-07-28
Start date
2015-04-01
Completion date
Unknown
Last updated
2020-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Insulin resistance Nutritional, Metabolic, Endocrine Insulin resistance

Interventions

All participants are encouraged to consume a Paleolithic diet for four weeks. This involves exclusion of grains, refined vegetable seed oils, refined sugar, dairy products, soya products and legumes
and replacing these foods with fruit, vegetables, root vegetables, fish, lean meat, eggs and nuts. All other foods can be consumed in unlimited quantities, but with no more than 30g nuts an 1 potato p

Sponsors

Dr Madhvi Chanrai
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Male or female 2. Age range 18 to 80 3. Healthy

Exclusion criteria

Exclusion criteria: Serious medical conditions.

Design outcomes

Secondary

MeasureTime frame
1. Fasting lipids is measured using analysis of blood samples at baseline and 4 weeks (2 weeks for those following the 2 week diet) 2. Fasting glucose is measured using analysis of blood samples at baseline and 4 weeks (2 weeks for those following the 2 week diet)

Primary

MeasureTime frame
1. Weight is measured in kg using a scale at home at baseline and 4 weeks (2 weeks for those following the 2 week diet) 2. Fasting insulin is measured using analysis of blood samples at baseline and 4 weeks (2 weeks for those following the 2 week diet) 3. Fasting leptin is measured using analysis of blood samples at baseline and 4 weeks (2 weeks for those following the 2 week diet)

Countries

India, United Kingdom

Contacts

Public ContactMadhvi Chanrai

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026