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A comparison of diets to treat moderate childhood malnutrition

Randomised controlled trial comparing the impacts of feeding with milk/peanut ready-to-use therapeutic food (RUTF), soy/peanut RUTF, and corn-soy blend (CSB) among children with moderate acute malnutrition in Malawi

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN47598408
Enrollment
1400
Registered
2008-05-12
Start date
2007-08-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Moderate malnutrition Nutritional, Metabolic, Endocrine Unspecified protein-energy malnutrition

Interventions

Feeding with one of three foods: 1. Ready-to-use milk/peanut fortified spread 2. Ready-to-use soy/peanut fortified spread 3. Corn soy blend Children will receive isoenergetic amounts of one of the ab
and the number of days of fever, cough and diarrhoea recorded from caretaker's report. Follow-up is for eight weeks.

Sponsors

Academy for Educational Development (AED) (USA)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Children aged 12 - 60 months 2. Moderate acute malnutrition using the World Health Organization (WHO) criteria (WHZ greater than -3 and less than -2) 3. Reside within 7 km 4. Present to one of seven supplementary feeding sites in southern Malawi during the study recruitment period

Exclusion criteria

Exclusion criteria: 1. Children who are not permanent residents in the vicinity of the local health centre (distance from home to health centre greater than 7 km) 2. Have severe chronic illnesses such as cerebral palsy 3. Have a history of peanut allergy or anaphylaxis resulting from any food 4. Receive other supplementary food from a government or charitable agency 5. Participating in another research study

Design outcomes

Primary

MeasureTime frame
Recovery, measured at the completion of the feeding period, usually eight weeks.

Secondary

MeasureTime frame
1. Weight gain, measured after four weeks 2. Height gain, measured after four weeks 3. Mid-upper arm circumference gain, measured after four weeks

Countries

Malawi

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026