Efficacy of the mode of delivery of autologous bone marrow cells into heart scar muscle for the recovery of contractile function

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN47591706

Enrollment

Registered

2005-09-30

Start date

2004-04-07

Completion date

Unknown

Last updated

2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery: Coronary artery bypass grafting (CABG) Surgery Coronary artery bypass grafting (CABG)

Interventions

[A] Control group receiving only myocardial revascularisation [B] Direct injection into the scar muscle of self bone marrow mononuclear cells in addition to myocardial revascularisation [C] Intravas

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing coronary bypass graft surgery aged between 18 and 80. Estimated 30 patients per group in order to detect significance

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

Measure	Time frame
Functional improvement, and reduction in size of scar areas. The study will also establish whether the number and the type of transplanted bone marrow mononuclear cells is correlated with the recovery of contractile function by performing multiple linear regression analysis.	—

Secondary

Measure	Time frame
Not provided at time of registration	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026