Lymphoma (non-Hodgkins) Cancer Lymphoma (non-Hodgkins)
Conditions
Interventions
1. Regimen CAPOMET: Combination chemotherapy with CAPOMET (cyclophosphamide, adriamycin, prednisolone, vincristine, methotrexate and etoposide). A weekly regimen repeated every 4 weeks with the more m
Sponsors
Cancer Research UK (CRUK) (UK)
Eligibility
Inclusion criteria
Inclusion criteria: 1. High grade pathology, malignant lymphoma classified as: Centroblastic; Lymphoblastic; Immunoblastic; True histocytic; High grade unclassified 2. Advanced (stage III or IV, extensive abdominal or otherwise bulky stage II disease) 3. No specific age limit but considered able to tolerate either treatment regimen 4. No previous radiotherapy, chemotherapy or immunotherapy 5. No previous malignancy, except adequately treated basal cell carcinoma or in-situ carcinoma of cervix 6. No serious medical or psychological condition precluding adequate treatment 7. Able to tolerate daily fluid intake of at least 2 litres 8. Ability of participating clinician to support patients with severe marrow hypoplasia
Exclusion criteria
Exclusion criteria: Not provided at time of registration
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Secondary
| Measure | Time frame |
|---|---|
| Not provided at time of registration | — |
Countries
United Kingdom
Outcome results
None listed