Lung resection Surgery Lung resection
Conditions
Interventions
There are three treatment arms:
1. Ropivacain
2. Remifentanil
3. Remifentanil plus Clonidin
These will be given as follows:
we perform neither pre- nor post-operative interventions. The follow up period amounts to three postoperative days.
Sponsors
Charité - University Medicine Berlin (Charité - Universitätsmedizin Berlin) (Germany)
Eligibility
Inclusion criteria
Inclusion criteria: Lung resection
Exclusion criteria
Exclusion criteria: 1. Patient under age 2. Pregnancy 3. Contraindications for epidural block 4. Contraindications for ropivacain 5. Contraindications for remifantanil 6. Contraindications for clonidine 9. Treatment with local anaesthetics 10. Treatment with central anti-adrenergic drugs (clonidine, methyldopa, moxonidine, reserpine) 11. Treatment with opioids 12. Myocardial Infarction (MI) within the last eight weeks 13. Cardiac insufficiency New York Heart Association (NYHA) III and IV
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Postoperative infections, measured immediately after surgery and in the first, second and third postoperative at rounds time in the morning. | — |
Primary
| Measure | Time frame |
|---|---|
| T1/T2 ratio, measured immediately after surgery and in the first, second and third postoperative at rounds time in the morning. | — |
Countries
Germany
Outcome results
None listed