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iHOST (Improving Hospital Opioid Substitution Therapy): An intervention to improve care for people who use opioids in NHS hospitals

Improving Hospital Opioid Substitution Therapy (iHOST): implementation and assessment of an intervention to reduce late presentations, discharges against medical advice and repeat admissions among people who use opioids

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN47320412
Enrollment
746
Registered
2022-07-11
Start date
2022-11-01
Completion date
Unknown
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Addiction, substance dependence Mental and Behavioural Disorders

Interventions

The iHOST toolkit comprises: 1. A ‘My Meds’ card. A prototype card has been developed with people who use opioids (PWUO). This provides information for hospital staff to prioritise and expedite medici
hospital pharmacy staff (n=~10). - We will conduct 1 additional workshop at Rele

Sponsors

London School of Hygiene & Tropical Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 110 Years

Inclusion criteria

Inclusion criteria: PWUO: 1. People who have a history of opioid use for non-medical reasons AND/OR are prescribed OST in a community setting for illicit opioid dependence 2. Aged 18 years or over 3. Assessed as capable to consent (not in debilitating withdrawal or intoxicated) 4. Presenting at A&E, an acute admissions ward or inpatient at one of the hospital sites OR a client at one of the linked drug treatment services Providers: 1. Healthcare staff involved in the prescribing, supply or administration of medicines to patients within A&E, acute admissions and high-burden inpatient wards 2. Staff at linked drug treatment services

Exclusion criteria

Exclusion criteria: 1. People who are under 18 years of age 2. In secure services 3. Lacking capacity for informed consent 4. No history of opioid dependence 5. (For providers) are not involved in OST-related service provision

Design outcomes

Primary

MeasureTime frame
Measured using patient records: 1. Discharge against medical advice (measured at hospital discharge) 2. Emergency readmission at any hospital in England (measured in the 28 days after discharge).

Secondary

MeasureTime frame
Measured using patient records: 1. Provision of opioid substitution therapy (OST) 2. Dose of OST 3. Duration between admission and provision of OST 4. Records of illicit substance use while admitted to hospital

Countries

England, United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 17, 2026