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Simvastatin (20 mg) vs ezetimibe (10 mg) plus simvastatin (20 mg) in subjects with hypercholesterolaemia and coronary heart disease (CHD)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN47214063
Enrollment
Unknown
Registered
2004-08-13
Start date
2000-04-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypercholesterolaemia and CHD Circulatory System

Interventions

Double-blind study involving 6 weeks treatment with a once daily dose of simvastatin (20 mg) plus either ezetimibe (10 mg) or matching ezetimibe placebo. Blood samples will be collected prior to treat

Sponsors

Schering-Plough UK Ltd
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Male or female subjects aged 18-75 years with screening low-density lipoprotein cholesterol (LDL-C) between 3.3 and 4.9 mmol/l

Exclusion criteria

Exclusion criteria: Not provided at time of registration

Design outcomes

Primary

MeasureTime frame
Not provided at time of registration—

Secondary

MeasureTime frame
Not provided at time of registration—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026