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The GPIAG/Leicester asthma and dysfunctional breathing project: The GLAD study (RESUBMITTED - PLEASE SEE UHL 8567)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN47153522
Enrollment
212
Registered
2003-09-12
Start date
2002-06-01
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthma Respiratory Asthma

Interventions

Breathing retraining supervised by a respiratory physiotherapist compared to an attention control of generic asthma education provided by a nurse.

Sponsors

Record provided by the NHS Trusts Clinical Trials Register - Department of Health (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Family practice patients? aged 18 - 65 years 2. A diagnosis of asthma 3. Received at least one asthma prescription in the previous year 4. With and without symptoms of dysfunctional breathing

Exclusion criteria

Exclusion criteria: Does not comply with above inclusion criteria

Design outcomes

Primary

MeasureTime frame
1. Asthma related quality of life (Juniper AQLQ) 2. Generic quality of life (Euroquol) 3. Asthma control (Juniper ACQ) 4. Nijmegen Questionnaire 5. Hospital Anxiety and Depression 6. Bronchial hyper-responsiveness (methacholine PC20) 7. Sputum eosinophil counts 8. Exhaled nitric oxide concentrations 9. Capnography 10. Hyperventilation studies Measured before and 1 month after the intervention and control procedures. The questionnaires will be re-administered 6 and 12 months following the completion of intervention.

Secondary

MeasureTime frame
No secondary outcome measures

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026